Research workbench
Crystal structure of mouse VPS26B(R240S/G241A/E242S) in spacegroup P41 21 2
Analyse Crystal structure of mouse VPS26B(R240S/G241A/E242S) in spacegroup P41 21 2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3LHA
- Type
- protein
- Length
- 565 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Vacuolar protein sorting-associated protein 26B
- UniProt
- Q8C0E2
- Pockets
- 9 · best druggability 0.64
Structure
x-ray diffraction · 2 distinct chains · 2% helix, 62% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Vacuolar protein sorting-associated protein 26B | protein | 283 | 2% helix, 63% strand | Q8C0E2 |
| B | Vacuolar protein sorting-associated protein 26B | protein | 282 | 2% helix, 61% strand | Q8C0E2 |
Pockets
9 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 454 | 0.64 | 0.77 | 54 | empty |
| 2 | 494 | 0.63 | 0.76 | 60 | empty |
| 3 | 196 | 0.51 | 0.77 | 31 | empty |
| 4 | 145 | 0.49 | 0.79 | 34 | empty |
| 5 | 104 | 0.42 | 0.78 | 24 | empty |
Interfaces
1 interface between chains.
- A–B · 1107 Ų buried · 17 hydrogen bonds · protein-protein
Compared structures
- 3LHA · Crystal structure of mouse VPS26B(R240S/G241A/E242S) in spacegroup P41 21 2 · the same entry in another collection · chain A against A, TM-score 1.00
- Q8C0E2 · AlphaFold monomer V2.0 prediction for vacuolar protein sorting- associated protein 26B… · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8C0E2
- Elsewhere: RCSB PDB 3LHA · PDBe 3LHA · UniProt Q8C0E2
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.