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Crystal structure of hpr dimer from thermoanaerobacter tengcongensis

Analyse Crystal structure of hpr dimer from thermoanaerobacter tengcongensis in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3LE5
Type: protein
Length: 174 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Phosphotransferase system, hpr-related proteins
UniProt: Q8R910
Pockets: 2 · best druggability 0.50

Structure

x-ray diffraction · 1 distinct chain · 37% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Phosphotransferase system, hpr-related proteins	protein	87	37% helix, 15% strand	Q8R910

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	168	0.50	0.77	20	empty
2	170	0.49	0.76	19	empty

Interfaces

1 interface between chains.

A–B · 330 Å² buried · 5 hydrogen bonds · protein-protein

Compared structures

3LE5 · Crystal structure of HPr dimer from Thermoanaerobacter tengcongensis · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8R910
Elsewhere: RCSB PDB 3LE5 · PDBe 3LE5 · UniProt Q8R910

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