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The crystal structure of the N-terminal domain of D- galactarate dehydratase from escherichia COLI CFT073

Analyse The crystal structure of the N-terminal domain of D- galactarate dehydratase… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3LAZ
Type: protein
Length: 192 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: D-galactarate dehydratase
EC: 4.2.1.42
UniProt: Q8FDB6
Pockets: 1 · best druggability 0.33

Structure

x-ray diffraction · 2 distinct chains · 5% helix, 31% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	D-galactarate dehydratase (EC 4.2.1.42)	protein	96	6% helix, 31% strand	Q8FDB6
B	D-galactarate dehydratase (EC 4.2.1.42)	protein	96	4% helix, 31% strand	Q8FDB6

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	85	0.33	0.74	19	empty

Interfaces

1 interface between chains.

A–B · 602 Å² buried · 9 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 modified (engineered).

Compared structures

3LAZ · The crystal structure of the N-terminal domain of D-galactarate dehydratase from… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8FDB6
Elsewhere: RCSB PDB 3LAZ · PDBe 3LAZ · UniProt Q8FDB6

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