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Crystal structure of SMU.1707C, a putative rRNA methyltransferase from streptococcus mutans UA159

Analyse Crystal structure of SMU.1707C, a putative rRNA methyltransferase from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3L8U
Type: protein
Length: 307 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative rRNA methylase
UniProt: Q8DSR4
Pockets: 6 · best druggability 0.64

Structure

x-ray diffraction · 2 distinct chains · 35% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Putative rRNA methylase	protein	154	34% helix, 20% strand	Q8DSR4
B	Putative rRNA methylase	protein	153	37% helix, 20% strand	Q8DSR4

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	250	0.64	0.82	26	empty
2	239	0.63	0.81	25	empty
3	113	0.49	0.81	27	empty
4	166	0.48	0.76	21	empty
5	76	0.38	0.78	15	empty

Interfaces

1 interface between chains.

A–B · 1379 Å² buried · 23 hydrogen bonds · protein-protein

Compared structures

3L8U · Crystal structure of SMU.1707c, a putative rRNA methyltransferase from streptococcus… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8DSR4
Elsewhere: RCSB PDB 3L8U · PDBe 3L8U · UniProt Q8DSR4

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