Research workbench
Structure of the reduced (feii) co-sensing protein from R. rubrum
Analyse Structure of the reduced (feii) co-sensing protein from R. rubrum in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1FT9
- Type
- protein
- Length
- 416 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Carbon monoxide oxidation system transcription regulator
- UniProt
- P72322
- Ligands
- HEM
- Pockets
- 7 · best druggability 0.71
Structure
x-ray diffraction · 2 distinct chains · 39% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Carbon monoxide oxidation system transcription regulator | protein | 210 | 38% helix, 24% strand | P72322 |
| B | Carbon monoxide oxidation system transcription regulator | protein | 206 | 40% helix, 25% strand | P72322 |
Ligands and binding sites
- HEM · Protoporphyrin IX containing Fe · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 168 | 0.71 | 0.89 | 29 | HEM |
| 2 | 145 | 0.62 | 0.84 | 22 | HEM |
| 3 | 176 | 0.52 | 0.78 | 23 | empty |
| 4 | 124 | 0.45 | 0.78 | 21 | empty |
| 5 | 97 | 0.36 | 0.74 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 1457 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 1FT9 · Structure of the reduced (feii) co-sensing protein from R. rubrum · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P72322
- Elsewhere: RCSB PDB 1FT9 · PDBe 1FT9 · UniProt P72322
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.