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Structure of split yeast PCNA

Analyse Structure of split yeast PCNA in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3L0X
Type: protein
Length: 254 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Proliferating cell nuclear antigen
UniProt: P15873
Pockets: 1 · best druggability 0.47

Structure

x-ray diffraction · 2 distinct chains · 19% helix, 43% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Proliferating cell nuclear antigen	protein	163	19% helix, 40% strand	P15873
B	Proliferating cell nuclear antigen	protein	91	18% helix, 48% strand	P15873

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	99	0.47	0.81	20	empty

Interfaces

1 interface between chains.

A–B · 3094 Å² buried · 64 hydrogen bonds · protein-protein

Compared structures

3L0X · Structure of split yeast PCNA · the same entry in another collection · chain A against A, TM-score 1.00
P15873 · AlphaFold monomer V2.0 prediction for proliferating cell nuclear antigen (P15873) · a predicted model of the same protein · chain B against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P15873
Elsewhere: RCSB PDB 3L0X · PDBe 3L0X · UniProt P15873

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