Research workbench
Crystal structure of ssgbp mutation variant G235S
Analyse Crystal structure of ssgbp mutation variant G235S in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3KXL
- Type
- protein
- Length
- 586 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- GTP-binding protein (hflx)
- UniProt
- Q980M3
- Ligands
- SCN
- Pockets
- 7 · best druggability 0.61
Structure
x-ray diffraction · 2 distinct chains · 46% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | GTP-binding protein (hflx) | protein | 295 | 46% helix, 21% strand | Q980M3 |
| B | GTP-binding protein (hflx) | protein | 291 | 46% helix, 21% strand | Q980M3 |
Ligands and binding sites
- SCN · Thiocyanate ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 242 | 0.61 | 0.81 | 46 | SCN |
| 2 | 163 | 0.55 | 0.81 | 36 | empty |
| 3 | 107 | 0.44 | 0.78 | 22 | empty |
| 4 | 57 | 0.36 | 0.79 | 17 | empty |
| 5 | 82 | 0.34 | 0.75 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 638 Ų buried · 2 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q980M3
- Elsewhere: RCSB PDB 3KXL · PDBe 3KXL · UniProt Q980M3
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