Research workbench
Mutant transport protein
Analyse Mutant transport protein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3KXC
- Type
- protein
- Length
- 292 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Trafficking protein particle complex subunit 3; Trafficking protein particle complex…
- UniProt
- O43617, Q86SZ2
- Ligands
- PLM
- Pockets
- 3 · best druggability 0.82
Structure
x-ray diffraction · 2 distinct chains · 50% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Trafficking protein particle complex subunit 3 | protein | 156 | 48% helix, 18% strand | O43617 |
| C | Trafficking protein particle complex subunit 6B | protein | 136 | 53% helix, 21% strand | Q86SZ2 |
Ligands and binding sites
- PLM · Palmitic acid · ligand · chains A, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 214 | 0.82 | 0.94 | 32 | PLM |
| 2 | 132 | 0.53 | 0.81 | 18 | empty |
| 3 | 214 | 0.51 | 0.76 | 22 | empty |
Interfaces
1 interface between chains.
- A–C · 1085 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 3KXC · Mutant transport protein · the same entry in another collection · chain A against A, TM-score 1.00
- O43617 · AlphaFold monomer V2.0 prediction for trafficking protein particle complex subunit 3… · a predicted model of the same protein · chain A against A, TM-score 0.96
- Q86SZ2 · AlphaFold monomer V2.0 prediction for trafficking protein particle complex subunit 6B… · a predicted model of the same protein · chain C against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O43617
- Every structure of UniProt Q86SZ2
- Elsewhere: RCSB PDB 3KXC · PDBe 3KXC · UniProt O43617 · UniProt Q86SZ2
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