Research workbench
X-ray structure of NS1 effector domain W187A mutant
Analyse X-ray structure of NS1 effector domain W187A mutant in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3KWG
- Type
- protein
- Length
- 255 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Non-structural protein 1
- UniProt
- P03495
- Pockets
- 3 · best druggability 0.43
Structure
x-ray diffraction · 2 distinct chains · 25% helix, 39% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Non-structural protein 1 | protein | 122 | 25% helix, 40% strand | P03495 |
| B | Non-structural protein 1 | protein | 133 | 26% helix, 38% strand | P03495 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 153 | 0.43 | 0.75 | 28 | empty |
| 2 | 105 | 0.43 | 0.78 | 23 | empty |
| 3 | 92 | 0.35 | 0.74 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 84 Ų buried · 1 hydrogen bond · protein-protein
Compared structures
- 3KWG · X-ray structure of NS1 effector domain W187A mutant · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03495
- Elsewhere: RCSB PDB 3KWG · PDBe 3KWG · UniProt P03495
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.