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Crystal structure of glycerol uptake operon antiterminator regulatory protein from listeria monocytogenes str. 4B F2365
Analyse Crystal structure of glycerol uptake operon antiterminator regulatory protein… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3KTS
- Type
- protein
- Length
- 1,474 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glycerol uptake operon antiterminator regulatory protein
- UniProt
- Q71ZR5
- Ligands
- UNL
- Pockets
- 20 · best druggability 0.68
Structure
x-ray diffraction · 4 distinct chains · 40% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, E, G, H | Glycerol uptake operon antiterminator regulatory protein | protein | 185 | 41% helix, 24% strand | Q71ZR5 |
| C | Glycerol uptake operon antiterminator regulatory protein | protein | 182 | 37% helix, 24% strand | Q71ZR5 |
| D | Glycerol uptake operon antiterminator regulatory protein | protein | 183 | 42% helix, 23% strand | Q71ZR5 |
| F | Glycerol uptake operon antiterminator regulatory protein | protein | 184 | 41% helix, 23% strand | Q71ZR5 |
Ligands and binding sites
- UNL · Unknown ligand · ligand · 8 copies · chains A, B, C, D, E, F, G, H
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
20 pockets found on a 1 Å grid, 11 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 616 | 0.68 | 0.77 | 52 | empty |
| 2 | 294 | 0.59 | 0.78 | 42 | UNL |
| 3 | 104 | 0.55 | 0.84 | 23 | UNL |
| 4 | 100 | 0.54 | 0.84 | 24 | UNL |
| 5 | 236 | 0.54 | 0.77 | 41 | UNL |
Interfaces
11 interfaces between chains.
- G–H · 845 Ų buried · 3 hydrogen bonds · protein-protein
- C–D · 828 Ų buried · 0 hydrogen bonds · protein-protein
- E–F · 822 Ų buried · 2 hydrogen bonds · protein-protein
- A–B · 805 Ų buried · 0 hydrogen bonds · protein-protein
- C–F · 707 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 3KTS · CRYSTAL STRUCTURE OF GLYCEROL UPTAKE OPERON ANTITERMINATOR REGULATORY PROTEIN FROM… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q71ZR5
- Elsewhere: RCSB PDB 3KTS · PDBe 3KTS · UniProt Q71ZR5
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