Research workbench
Crystal structure of reston ebolavirus VP35 RNA binding domain
Analyse Crystal structure of reston ebolavirus VP35 RNA binding domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3KS4
- Type
- protein
- Length
- 249 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Polymerase cofactor VP35
- UniProt
- Q8JPY0
- Pockets
- 1 · best druggability 0.38
Structure
x-ray diffraction · 2 distinct chains · 52% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Polymerase cofactor VP35 | protein | 125 | 51% helix, 14% strand | Q8JPY0 |
| B | Polymerase cofactor VP35 | protein | 124 | 52% helix, 14% strand | Q8JPY0 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 103 | 0.38 | 0.75 | 26 | empty |
Interfaces
1 interface between chains.
- A–B · 496 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
- 3KS4 · Crystal structure of Reston ebolavirus VP35 RNA binding domain · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8JPY0
- Elsewhere: RCSB PDB 3KS4 · PDBe 3KS4 · UniProt Q8JPY0
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