Research workbench
Structure of triosephosphate isomerase from cryptosporidium parvum at 1.55A resolution
Analyse Structure of triosephosphate isomerase from cryptosporidium parvum at 1.55A… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3KRS
- Type
- protein
- Length
- 498 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Triosephosphate isomerase
- EC
- 5.3.1.1
- UniProt
- Q5CSE7
- Ligands
- NA, UNX
- Pockets
- 4 · best druggability 0.74
Structure
x-ray diffraction · 1 distinct chain · 43% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Triosephosphate isomerase (EC 5.3.1.1) | protein | 249 | 43% helix, 15% strand | Q5CSE7 |
Ligands and binding sites
- NA · Sodium ion · metal · 2 copies · chains A, B
- UNX · Unknown atom or ion · ion · 12 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 101 | 0.74 | 0.96 | 25 | empty |
| 2 | 128 | 0.49 | 0.79 | 25 | empty |
| 3 | 115 | 0.39 | 0.75 | 30 | UNX |
| 4 | 92 | 0.38 | 0.76 | 21 | UNX |
Interfaces
1 interface between chains.
- A–B · 1677 Ų buried · 30 hydrogen bonds · protein-protein
Compared structures
- 3KRS · Structure of Triosephosphate Isomerase from Cryptosporidium Parvum at 1.55A Resolution · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5CSE7
- Elsewhere: RCSB PDB 3KRS · PDBe 3KRS · UniProt Q5CSE7
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.