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Circular permutant of the tobacco mosaic virus

Analyse Circular permutant of the tobacco mosaic virus in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3KML
Type: protein
Length: 2,397 residues
Chains: 17
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Coat protein
UniProt: P69687
Pockets: 17 · best druggability 0.33

Structure

x-ray diffraction · 1 distinct chain · 48% helix, 11% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q	Coat protein	protein	141	48% helix, 11% strand	P69687

Pockets

17 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	83	0.33	0.74	18	empty
2	80	0.32	0.74	18	empty
3	84	0.32	0.74	18	empty
4	78	0.32	0.74	18	empty
5	73	0.32	0.74	18	empty

Interfaces

17 interfaces between chains.

D–Q · 1157 Å² buried · 15 hydrogen bonds · protein-protein
M–P · 1156 Å² buried · 14 hydrogen bonds · protein-protein
C–D · 1155 Å² buried · 12 hydrogen bonds · protein-protein
H–O · 1154 Å² buried · 15 hydrogen bonds · protein-protein
F–Q · 1153 Å² buried · 14 hydrogen bonds · protein-protein

Compared structures

3KML · Circular Permutant of the Tobacco Mosaic Virus · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P69687
Elsewhere: RCSB PDB 3KML · PDBe 3KML · UniProt P69687

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