Research workbench
Crystal structure of functionally unknown HSP33 from saccharomyces cerevisiae
Analyse Crystal structure of functionally unknown HSP33 from saccharomyces cerevisiae in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3KKL
- Type
- protein
- Length
- 431 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Probable chaperone protein HSP33
- EC
- 3.2.-.-
- UniProt
- Q08914
- Pockets
- 5 · best druggability 0.59
Structure
x-ray diffraction · 2 distinct chains · 38% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Probable chaperone protein HSP33 (EC 3.2.-.-) | protein | 215 | 38% helix, 18% strand | Q08914 |
| B | Probable chaperone protein HSP33 (EC 3.2.-.-) | protein | 216 | 38% helix, 19% strand | Q08914 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 429 | 0.59 | 0.75 | 44 | empty |
| 2 | 97 | 0.47 | 0.80 | 19 | empty |
| 3 | 69 | 0.32 | 0.75 | 16 | empty |
| 4 | 60 | 0.30 | 0.75 | 13 | empty |
| 5 | 57 | 0.29 | 0.75 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 575 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 3KKL · Crystal structure of functionally unknown HSP33 from Saccharomyces cerevisiae · the same entry in another collection · chain A against A, TM-score 1.00
- Q08914 · AlphaFold monomer V2.0 prediction for probable glutathione- independent glyoxalase HSP33… · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q08914
- Elsewhere: RCSB PDB 3KKL · PDBe 3KKL · UniProt Q08914
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