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Crystal structure of S. pombe STN1-TEN1 complex

Analyse Crystal structure of S. pombe STN1-TEN1 complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
3KF6
Type
protein
Length
241 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Protein STN1; Protein TEN1
UniProt
Q0E7J7, P0C5Y7
Pockets
3 · best druggability 0.63

Structure

x-ray diffraction · 2 distinct chains · 24% helix, 41% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AProtein STN1protein13628% helix, 40% strandQ0E7J7
BProtein TEN1protein10518% helix, 43% strandP0C5Y7

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11120.630.8821empty
21120.410.7623empty
3610.280.7315empty

Interfaces

1 interface between chains.

  • A–B · 1013 Ų buried · 19 hydrogen bonds · protein-protein

Compared structures

  • 3KF6 · Crystal structure of S. pombe Stn1-ten1 complex · the same entry in another collection · chain A against A, TM-score 1.00
  • Q0E7J7 · AlphaFold monomer V2.0 prediction for protein STN1 (Q0E7J7) · a predicted model of the same protein · chain A against A, TM-score 0.99
  • P0C5Y7 · AlphaFold monomer V2.0 prediction for protein TEN1 (P0C5Y7) · a predicted model of the same protein · chain B against A, TM-score 0.91

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