Research workbench
Crystal structure of RV3671C protease, inactive form
Analyse Crystal structure of RV3671C protease, inactive form in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3K6Z
- Type
- protein
- Length
- 395 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Possible membrane-associated serine protease
- EC
- 3.4.21.-
- UniProt
- O69639
- Pockets
- 2 · best druggability 0.70
Structure
x-ray diffraction · 2 distinct chains · 17% helix, 44% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Possible membrane-associated serine protease (EC 3.4.21.-) | protein | 198 | 17% helix, 43% strand | O69639 |
| B | Possible membrane-associated serine protease (EC 3.4.21.-) | protein | 197 | 17% helix, 44% strand | O69639 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 155 | 0.70 | 0.90 | 22 | empty |
| 2 | 127 | 0.46 | 0.78 | 23 | empty |
Interfaces
1 interface between chains.
- A–B · 941 Ų buried · 10 hydrogen bonds · protein-protein
Compared structures
- 3K6Z · Crystal structure of Rv3671c protease, inactive form · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O69639
- Elsewhere: RCSB PDB 3K6Z · PDBe 3K6Z · UniProt O69639
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