Research workbench

Crystal structure of recombinant farnesyl diphosphate synthase at 2.6 ångströms resolution

Analyse Crystal structure of recombinant farnesyl diphosphate synthase at 2.6 ångströms… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1FPS
Type: protein
Length: 348 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Farnesyl diphosphate synthase
EC: 2.5.1.10
UniProt: P08836
Pockets: 5 · best druggability 0.78

Structure

x-ray diffraction · 1 distinct chain · 68% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Farnesyl diphosphate synthase (EC 2.5.1.10)	protein	348	68% helix, 1% strand	P08836

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1032	0.78	0.80	70	empty
2	120	0.50	0.80	18	empty
3	75	0.32	0.74	14	empty
4	52	0.30	0.76	16	empty
5	63	0.28	0.73	12	empty

Compared structures

1FPS · Crystal structure of recombinant farnesyl diphosphate synthase at 2.6 ångströms resolution · the same entry in another collection · chain A against A, TM-score 1.00
P08836 · AlphaFold monomer V2.0 prediction for farnesyl pyrophosphate synthase (P08836) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P08836
Elsewhere: RCSB PDB 1FPS · PDBe 1FPS · UniProt P08836

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.