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Crystal structure of the eukaryotic strong inward-rectifier K+ channel KIR2.2 at 3.1 ångström resolution
Analyse Crystal structure of the eukaryotic strong inward-rectifier K+ channel KIR2.2… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3JYC
- Type
- protein
- Length
- 321 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Inward-rectifier K+ channel KIR2.2
- Ligands
- K
- Pockets
- 3 · best druggability 0.32
Structure
x-ray diffraction · 1 distinct chain · 28% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Inward-rectifier K+ channel KIR2.2 | protein | 321 | 28% helix, 28% strand | — |
Ligands and binding sites
- K · Potassium ion · metal · 5 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 59 | 0.32 | 0.76 | 14 | empty |
| 2 | 58 | 0.31 | 0.76 | 22 | empty |
| 3 | 61 | 0.26 | 0.72 | 14 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 3JYC · Crystal structure of the eukaryotic strong inward-rectifier K+ channel Kir2.2 at 3.1… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 3JYC · PDBe 3JYC
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