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Crystal structure analysis of the methyltransferase domain of bacterial-CTHEN1-cn
Analyse Crystal structure analysis of the methyltransferase domain of… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3JWI
- Type
- protein
- Length
- 388 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Methyltransferase type 12
- UniProt
- A3DJ37
- Pockets
- 4 · best druggability 0.47
Structure
x-ray diffraction · 2 distinct chains · 42% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Methyltransferase type 12 | protein | 195 | 41% helix, 23% strand | A3DJ37 |
| B | Methyltransferase type 12 | protein | 193 | 44% helix, 24% strand | A3DJ37 |
Pockets
4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 152 | 0.47 | 0.77 | 24 | empty |
| 2 | 64 | 0.41 | 0.81 | 15 | empty |
| 3 | 108 | 0.40 | 0.76 | 24 | empty |
| 4 | 63 | 0.29 | 0.74 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 644 Ų buried · 17 hydrogen bonds · protein-protein
Compared structures
- 3JWI · Crystal structure analysis of the methyltransferase domain of bacterial-CtHen1-CN · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A3DJ37
- Elsewhere: RCSB PDB 3JWI · PDBe 3JWI · UniProt A3DJ37
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