Research workbench
3-deoxy-manno-octulosonate cytidylyltransferase from yersinia pestis
Analyse 3-deoxy-manno-octulosonate cytidylyltransferase from yersinia pestis in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3JTJ
- Type
- protein
- Length
- 249 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 3-deoxy-manno-octulosonate cytidylyltransferase
- EC
- 2.7.7.38
- UniProt
- Q8ZGA4
- Pockets
- 2 · best druggability 0.54
Structure
x-ray diffraction · 1 distinct chain · 35% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 3-deoxy-manno-octulosonate cytidylyltransferase (EC 2.7.7.38) | protein | 249 | 35% helix, 22% strand | Q8ZGA4 |
Ligands and binding sites
- IMD · Imidazole · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 271 | 0.54 | 0.76 | 37 | IMD |
| 2 | 64 | 0.37 | 0.79 | 19 | empty |
Modifications
Observed in the structure: 5 modified (engineered).
Compared structures
- 3JTJ · 3-deoxy-manno-octulosonate cytidylyltransferase from Yersinia pestis · the same entry in another collection · chain A against A, TM-score 1.00
- Q8ZGA4 · AlphaFold monomer V2.0 prediction for 3-deoxy-manno-octulosonate cytidylyltransferase… · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8ZGA4
- Elsewhere: RCSB PDB 3JTJ · PDBe 3JTJ · UniProt Q8ZGA4
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