Research workbench
Homoserine dehydrogenase from thermoplasma volcanium complexed with NAD
Analyse Homoserine dehydrogenase from thermoplasma volcanium complexed with NAD in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3JSA
- Type
- protein
- Length
- 321 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Homoserine dehydrogenase
- UniProt
- Q97BR6
- Ligands
- NAD, SO4
- Pockets
- 2 · best druggability 0.59
Structure
x-ray diffraction · 1 distinct chain · 42% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Homoserine dehydrogenase | protein | 321 | 42% helix, 22% strand | Q97BR6 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 387 | 0.59 | 0.76 | 39 | NAD |
| 2 | 55 | 0.26 | 0.73 | 16 | empty |
Modifications
Observed in the structure: 4 modified (engineered).
Compared structures
- 3JSA · Homoserine dehydrogenase from Thermoplasma volcanium complexed with NAD · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q97BR6
- Elsewhere: RCSB PDB 3JSA · PDBe 3JSA · UniProt Q97BR6
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