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Structure of T7 gatekeeper protein (GP11)

Analyse Structure of T7 gatekeeper protein (GP11) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3J4B
Type: protein
Length: 2,208 residues
Chains: 12
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Tail tubular protein a
UniProt: P03746
Pockets: 14 · best druggability 0.46

Structure

electron microscopy · 1 distinct chain · 0% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, J, K, L, B, C, D, E, F, G, H, I	Tail tubular protein a	protein	184	0% helix, 0% strand	P03746

Pockets

14 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	153	0.46	0.74	39	empty
2	136	0.44	0.74	39	empty
3	124	0.43	0.74	35	empty
4	122	0.42	0.74	33	empty
5	141	0.42	0.73	42	empty

Interfaces

12 interfaces between chains.

F–G · 18 Å² buried · 0 hydrogen bonds · protein-protein
E–F · 17 Å² buried · 0 hydrogen bonds · protein-protein
G–H · 17 Å² buried · 0 hydrogen bonds · protein-protein
C–D · 17 Å² buried · 0 hydrogen bonds · protein-protein
K–L · 17 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

3J4B · Structure of T7 gatekeeper protein (gp11) · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P03746
Elsewhere: RCSB PDB 3J4B · PDBe 3J4B · UniProt P03746

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