Research workbench
Structure of aav-dj, a retargeted gene therapy vector: cryo-electron microscopy at 4.5A resolution
Analyse Structure of aav-dj, a retargeted gene therapy vector: cryo-electron microscopy… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3J1Q
- Type
- protein
- Length
- 517 residues
- Chains
- 1
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Adeno-associated virus dj
- Pockets
- 7 · best druggability 0.58
Structure
electron microscopy · 1 distinct chain · 4% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Adeno-associated virus dj | protein | 517 | 4% helix, 33% strand | — |
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 325 | 0.58 | 0.76 | 45 | empty |
| 2 | 331 | 0.56 | 0.75 | 43 | empty |
| 3 | 202 | 0.45 | 0.74 | 26 | empty |
| 4 | 81 | 0.37 | 0.77 | 16 | empty |
| 5 | 96 | 0.35 | 0.74 | 15 | empty |
Compared structures
- 3J1Q · Structure of AAV-DJ, a Retargeted Gene Therapy Vector: Cryo-Electron Microscopy at 4.5A… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 3J1Q · PDBe 3J1Q
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.