Research workbench

Bacteriophage T7 prohead shell EM-derived atomic model

Analyse Bacteriophage T7 prohead shell EM-derived atomic model in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3IZG
Type: protein
Length: 1,722 residues
Chains: 7
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Major capsid protein 10A
UniProt: P19726
Pockets: 20 · best druggability 0.73

Structure

electron microscopy · 1 distinct chain · 22% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
G, A, B, C, D, E, F	Major capsid protein 10A	protein	246	22% helix, 15% strand	P19726

Pockets

20 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	749	0.73	0.79	96	empty
2	560	0.72	0.81	73	empty
3	556	0.72	0.81	67	empty
4	461	0.69	0.80	64	empty
5	455	0.68	0.80	48	empty

Interfaces

9 interfaces between chains.

B–C · 1395 Å² buried · 14 hydrogen bonds · protein-protein
E–F · 1295 Å² buried · 14 hydrogen bonds · protein-protein
A–F · 1193 Å² buried · 9 hydrogen bonds · protein-protein
C–D · 1146 Å² buried · 9 hydrogen bonds · protein-protein
A–B · 556 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

3IZG · Bacteriophage T7 prohead shell EM-derived atomic model · the same entry in another collection · chain D against D, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P19726
Elsewhere: RCSB PDB 3IZG · PDBe 3IZG · UniProt P19726

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.