Research workbench
Crystal structure of activating signal cointegrator (NP_814290.1) from enterococcus faecalis V583 at 1.58 a resolution
Analyse Crystal structure of activating signal cointegrator (NP_814290.1) from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3IUW
- Type
- protein
- Length
- 159 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Activating signal cointegrator
- UniProt
- Q8KUB7
- Ligands
- SO4
- Pockets
- 2 · best druggability 0.42
Structure
x-ray diffraction · 2 distinct chains · 10% helix, 54% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Activating signal cointegrator | protein | 79 | 10% helix, 54% strand | Q8KUB7 |
| B | Activating signal cointegrator | protein | 80 | 10% helix, 54% strand | Q8KUB7 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 76 | 0.42 | 0.79 | 16 | empty |
| 2 | 75 | 0.36 | 0.76 | 13 | CAC |
Interfaces
1 interface between chains.
- A–B · 931 Ų buried · 10 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 modified (engineered).
Compared structures
- 3IUW · Crystal structure of Activating signal cointegrator (NP_814290.1) from ENTEROCOCCUS… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8KUB7
- Elsewhere: RCSB PDB 3IUW · PDBe 3IUW · UniProt Q8KUB7
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