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Crystal structure of functional region of uafa from staphylococcus saprophyticus in C2 form at 2.45 ångström resolution

Analyse Crystal structure of functional region of uafa from staphylococcus… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3IS1
Type: protein
Length: 393 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Uro-adherence factor a
UniProt: Q4A0V8
Pockets: 3 · best druggability 0.56

Structure

x-ray diffraction · 1 distinct chain · 6% helix, 54% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
X	Uro-adherence factor a	protein	393	6% helix, 54% strand	Q4A0V8

Ligands and binding sites

GOL · Glycerol · additive · chains X

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	321	0.56	0.76	47	empty
2	133	0.53	0.82	29	empty
3	65	0.30	0.74	13	empty

Compared structures

3IS1 · Crystal structure of functional region of UafA from Staphylococcus saprophyticus in C2… · the same entry in another collection · chain X against X, TM-score 1.00
Q4A0V8 · AlphaFold monomer V2.0 prediction for uro-adherence factor a (Q4A0V8) · a predicted model of the same protein · chain X against A, TM-score 0.96

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Every structure of UniProt Q4A0V8
Elsewhere: RCSB PDB 3IS1 · PDBe 3IS1 · UniProt Q4A0V8

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