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Amppnp complex of C. therm. GET3

Analyse Amppnp complex of C. therm. GET3 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3IQW
Type: protein
Length: 515 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Tail-anchored protein targeting factor GET3
Ligands: ANP, MG, ZN
Pockets: 3 · best druggability 0.89

Structure

x-ray diffraction · 2 distinct chains · 45% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tail-anchored protein targeting factor GET3	protein	260	45% helix, 17% strand	—
B	Tail-anchored protein targeting factor GET3	protein	255	44% helix, 17% strand	—

Ligands and binding sites

ANP · Phosphoaminophosphonic acid-adenylate ester · ligand · 2 copies · chains A, B
MG · Magnesium ion · metal · 2 copies · chains A, B
ZN · Zinc ion · metal · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1122	0.89	0.91	114	ANP, MG
2	80	0.33	0.74	17	empty
3	72	0.32	0.74	18	empty

Interfaces

1 interface between chains.

A–B · 1442 Å² buried · 15 hydrogen bonds · protein-protein

Compared structures

3IQW · AMPPNP complex of C. therm. Get3 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 3IQW · PDBe 3IQW

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