Research workbench
Human sorting nexin 7, phox homology (px) domain
Analyse Human sorting nexin 7, phox homology (px) domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3IQ2
- Type
- protein
- Length
- 246 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Sorting nexin-7
- UniProt
- Q9UNH6
- Ligands
- SO4
- Pockets
- 5 · best druggability 0.47
Structure
x-ray diffraction · 1 distinct chain · 39% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Sorting nexin-7 | protein | 123 | 39% helix, 25% strand | Q9UNH6 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 146 | 0.47 | 0.77 | 18 | empty |
| 2 | 88 | 0.45 | 0.80 | 15 | SO4 |
| 3 | 94 | 0.42 | 0.78 | 13 | SO4 |
| 4 | 85 | 0.36 | 0.76 | 17 | empty |
| 5 | 90 | 0.33 | 0.73 | 20 | empty |
Interfaces
1 interface between chains.
- A–B · 1008 Ų buried · 16 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UNH6
- Elsewhere: RCSB PDB 3IQ2 · PDBe 3IQ2 · UniProt Q9UNH6
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