Research workbench
Crystal structure analysis of mglu in its tris form
Analyse Crystal structure analysis of mglu in its tris form in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3IH9
- Type
- protein
- Length
- 896 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Salt-tolerant glutaminase
- EC
- 3.5.1.2
- UniProt
- Q4U1A6
- Pockets
- 11 · best druggability 0.63
Structure
x-ray diffraction · 1 distinct chain · 46% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Salt-tolerant glutaminase (EC 3.5.1.2) | protein | 448 | 46% helix, 16% strand | Q4U1A6 |
Pockets
11 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 405 | 0.63 | 0.77 | 41 | empty |
| 2 | 398 | 0.63 | 0.78 | 35 | empty |
| 3 | 233 | 0.47 | 0.74 | 34 | empty |
| 4 | 220 | 0.46 | 0.73 | 38 | empty |
| 5 | 65 | 0.41 | 0.80 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 729 Ų buried · 23 hydrogen bonds · protein-protein
Compared structures
- 3IH9 · Crystal Structure Analysis of Mglu in its tris form · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q4U1A6
- Elsewhere: RCSB PDB 3IH9 · PDBe 3IH9 · UniProt Q4U1A6
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.