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Crystal structure of an uncharacterized metal-dependent hydrolase from pyrococcus furiosus

Analyse Crystal structure of an uncharacterized metal-dependent hydrolase from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3ICJ
Type: protein
Length: 468 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Uncharacterized metal-dependent hydrolase
UniProt: Q8U2I8
Ligands: ZN
Pockets: 3 · best druggability 0.71

Structure

x-ray diffraction · 1 distinct chain · 39% helix, 24% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Uncharacterized metal-dependent hydrolase	protein	468	39% helix, 24% strand	Q8U2I8

Ligands and binding sites

ZN · Zinc ion · metal · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	832	0.71	0.76	59	empty
2	83	0.40	0.78	16	empty
3	91	0.33	0.74	18	empty

Modifications

Observed in the structure: 1 modified (carboxylation).

Compared structures

3ICJ · Crystal structure of an uncharacterized metal-dependent hydrolase from pyrococcus furiosus · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8U2I8
Elsewhere: RCSB PDB 3ICJ · PDBe 3ICJ · UniProt Q8U2I8

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