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Crystal structure of putative transcriptional regulator of gntr family from bacteroides thetaiotaomicron

Analyse Crystal structure of putative transcriptional regulator of gntr family from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3IC7
Type: protein
Length: 224 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative transcriptional regulator
UniProt: Q8A870
Pockets: 3 · best druggability 0.44

Structure

x-ray diffraction · 2 distinct chains · 54% helix, 10% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Putative transcriptional regulator	protein	113	55% helix, 10% strand	Q8A870
B	Putative transcriptional regulator	protein	111	54% helix, 10% strand	Q8A870

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	83	0.44	0.80	13	empty
2	175	0.43	0.74	30	empty
3	67	0.36	0.77	13	empty

Interfaces

1 interface between chains.

A–B · 136 Å² buried · 0 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 6 modified (engineered).

Compared structures

3IC7 · Crystal Structure of Putative Transcriptional Regulator of GntR Family from Bacteroides… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8A870
Elsewhere: RCSB PDB 3IC7 · PDBe 3IC7 · UniProt Q8A870

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