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N-terminal domain of putative saccharopine dehydrogenase from ruegeria pomeroyi.

Analyse N-terminal domain of putative saccharopine dehydrogenase from ruegeria pomeroyi. in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3IC5
Type: protein
Length: 230 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative saccharopine dehydrogenase
UniProt: Q5LX24
Pockets: 4 · best druggability 0.52

Structure

x-ray diffraction · 2 distinct chains · 43% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Putative saccharopine dehydrogenase	protein	115	45% helix, 21% strand	Q5LX24
B	Putative saccharopine dehydrogenase	protein	115	42% helix, 21% strand	Q5LX24

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	128	0.52	0.81	30	empty
2	58	0.39	0.81	17	empty
3	102	0.37	0.74	16	empty
4	50	0.25	0.73	13	empty

Interfaces

1 interface between chains.

A–B · 826 Å² buried · 5 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 6 modified (engineered).

Compared structures

3IC5 · N-terminal domain of putative saccharopine dehydrogenase from Ruegeria pomeroyi. · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5LX24
Elsewhere: RCSB PDB 3IC5 · PDBe 3IC5 · UniProt Q5LX24

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