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Crystal structure of the P60 domain from M. avium subspecies paratuberculosis antigen MAP1204

Analyse Crystal structure of the P60 domain from M. avium subspecies paratuberculosis… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3I86
Type: protein
Length: 274 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative uncharacterized protein
EC: 3.4.19.11
UniProt: Q740Y8
Pockets: 1 · best druggability 0.61

Structure

x-ray diffraction · 2 distinct chains · 28% helix, 28% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Putative uncharacterized protein (EC 3.4.19.11)	protein	136	29% helix, 29% strand	Q740Y8
B	Putative uncharacterized protein (EC 3.4.19.11)	protein	138	28% helix, 26% strand	Q740Y8

Ligands and binding sites

IPA · Isopropyl alcohol · additive · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	487	0.61	0.75	41	empty

Interfaces

1 interface between chains.

A–B · 507 Å² buried · 5 hydrogen bonds · protein-protein

Compared structures

3I86 · Crystal structure of the P60 Domain from M. avium subspecies paratuberculosis antigen… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q740Y8
Elsewhere: RCSB PDB 3I86 · PDBe 3I86 · UniProt Q740Y8

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