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Crystal structure of CAS6 in pyrococcus furiosus

Analyse Crystal structure of CAS6 in pyrococcus furiosus in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3I4H
Type: protein
Length: 232 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Endoribonuclease
UniProt: Q8U1S4
Pockets: 2 · best druggability 0.42

Structure

x-ray diffraction · 1 distinct chain · 29% helix, 35% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
X	Endoribonuclease	protein	232	29% helix, 35% strand	Q8U1S4

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	125	0.42	0.76	19	empty
2	53	0.27	0.73	10	empty

Compared structures

3I4H · Crystal structure of Cas6 in Pyrococcus furiosus · the same entry in another collection · chain X against X, TM-score 1.00
Q8U1S4 · AlphaFold monomer V2.0 prediction for CRISPR-associated endoribonuclease CAS6 (Q8U1S4) · a predicted model of the same protein · chain X against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8U1S4
Elsewhere: RCSB PDB 3I4H · PDBe 3I4H · UniProt Q8U1S4

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