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Crystal structure of transcription regulator like protein from staphylococcus haemolyticus
Analyse Crystal structure of transcription regulator like protein from staphylococcus… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3HUU
- Type
- protein
- Length
- 1,057 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transcription regulator like protein
- UniProt
- Q4L6K9
- Pockets
- 9 · best druggability 0.79
Structure
x-ray diffraction · 4 distinct chains · 42% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transcription regulator like protein | protein | 265 | 42% helix, 19% strand | Q4L6K9 |
| B | Transcription regulator like protein | protein | 260 | 42% helix, 20% strand | Q4L6K9 |
| C | Transcription regulator like protein | protein | 267 | 42% helix, 19% strand | Q4L6K9 |
| D | Transcription regulator like protein | protein | 265 | 43% helix, 20% strand | Q4L6K9 |
Pockets
9 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 154 | 0.79 | 0.95 | 32 | empty |
| 2 | 103 | 0.77 | 0.97 | 31 | empty |
| 3 | 84 | 0.75 | 0.97 | 33 | empty |
| 4 | 276 | 0.74 | 0.87 | 42 | empty |
| 5 | 305 | 0.73 | 0.86 | 44 | empty |
Interfaces
2 interfaces between chains.
- A–B · 1980 Ų buried · 33 hydrogen bonds · protein-protein
- C–D · 1970 Ų buried · 32 hydrogen bonds · protein-protein
Compared structures
- 3HUU · Crystal structure of transcription regulator like protein from Staphylococcus haemolyticus · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q4L6K9
- Elsewhere: RCSB PDB 3HUU · PDBe 3HUU · UniProt Q4L6K9
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