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Intersectin 1-peptide-AP2 alpha ear complex

Analyse Intersectin 1-peptide-AP2 alpha ear complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
3HS8
Type
protein
Length
250 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Adaptor protein complex ap-2, alpha 2 subunit; Peptide from intersectin-1, residues…
UniProt
Q6PEE6, Q9Z0R4

Structure

x-ray diffraction · 2 distinct chains · 19% helix, 41% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AAdaptor protein complex ap-2, alpha 2 subunitprotein23820% helix, 43% strandQ6PEE6
PPeptide from intersectin-1, residues 840-851protein120% helix, 0% strandQ9Z0R4

Interfaces

1 interface between chains.

  • A–P · 416 Ų buried · 9 hydrogen bonds · protein-protein

Compared structures

  • 3HS8 · Intersectin 1-peptide-AP2 alpha ear complex · the same entry in another collection · chain A against A, TM-score 1.00
  • Q9Z0R4 · AlphaFold monomer V2.0 prediction for intersectin-1 (Q9Z0R4) · a predicted model of the same protein · chain P against A, TM-score 0.28

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