Research workbench
Structure of halothermothrix orenii fructokinase (frk)
Analyse Structure of halothermothrix orenii fructokinase (frk) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3HJ6
- Type
- protein
- Length
- 556 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fructokinase
- EC
- 2.7.1.4
- UniProt
- B8CZ52
- Pockets
- 5 · best druggability 0.60
Structure
x-ray diffraction · 1 distinct chain · 35% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Fructokinase (EC 2.7.1.4) | protein | 278 | 35% helix, 22% strand | B8CZ52 |
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 408 | 0.60 | 0.76 | 42 | empty |
| 2 | 400 | 0.60 | 0.76 | 41 | empty |
| 3 | 247 | 0.53 | 0.76 | 31 | empty |
| 4 | 56 | 0.30 | 0.76 | 13 | empty |
| 5 | 54 | 0.29 | 0.75 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 1084 Ų buried · 20 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 modified (engineered).
Compared structures
- 3HJ6 · Structure of Halothermothrix orenii fructokinase (FRK) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B8CZ52
- Elsewhere: RCSB PDB 3HJ6 · PDBe 3HJ6 · UniProt B8CZ52
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