Research workbench

SAM domain of human ephrin type-a receptor 1 (EPHA1)

Analyse SAM domain of human ephrin type-a receptor 1 (EPHA1) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3HIL
Type: protein
Length: 125 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ephrin type-a receptor 1
EC: 2.7.10.1
UniProt: P21709
Ligands: CL, NO3

Structure

x-ray diffraction · 2 distinct chains · 62% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ephrin type-a receptor 1 (EC 2.7.10.1)	protein	63	62% helix, 0% strand	P21709
B	Ephrin type-a receptor 1 (EC 2.7.10.1)	protein	62	61% helix, 0% strand	P21709

Ligands and binding sites

CL · Chloride ion · ion · chains A
NO3 · Nitrate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

A–B · 589 Å² buried · 12 hydrogen bonds · protein-protein

Compared structures

3HIL · SAM Domain of Human Ephrin Type-A Receptor 1 (EphA1) · the same entry in another collection · chain A against A, TM-score 1.00
P21709 · AlphaFold monomer V2.0 prediction for ephrin type-a receptor 1 (P21709) · a predicted model of the same protein · chain B against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P21709
Elsewhere: RCSB PDB 3HIL · PDBe 3HIL · UniProt P21709

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.