Research workbench
Crystal structure of response regulator receiver protein from pseudomonas putida
Analyse Crystal structure of response regulator receiver protein from pseudomonas putida in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3HDV
- Type
- protein
- Length
- 484 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Response regulator
- UniProt
- Q88QX9
- Pockets
- 4 · best druggability 0.51
Structure
x-ray diffraction · 4 distinct chains · 42% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Response regulator | protein | 120 | 44% helix, 21% strand | Q88QX9 |
| B | Response regulator | protein | 126 | 41% helix, 21% strand | Q88QX9 |
| C | Response regulator | protein | 121 | 41% helix, 21% strand | Q88QX9 |
| D | Response regulator | protein | 117 | 42% helix, 21% strand | Q88QX9 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 76 | 0.51 | 0.84 | 19 | empty |
| 2 | 116 | 0.51 | 0.81 | 26 | empty |
| 3 | 55 | 0.43 | 0.83 | 17 | empty |
| 4 | 58 | 0.43 | 0.82 | 14 | empty |
Interfaces
3 interfaces between chains.
- A–C · 524 Ų buried · 2 hydrogen bonds · protein-protein
- B–D · 515 Ų buried · 2 hydrogen bonds · protein-protein
- B–C · 475 Ų buried · 0 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 12 modified (engineered).
Compared structures
- 3HDV · Crystal structure of response regulator receiver protein from Pseudomonas putida · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q88QX9
- Elsewhere: RCSB PDB 3HDV · PDBe 3HDV · UniProt Q88QX9
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.