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Crystal structure of chicken sulfite oxidase mutant tyr 322 phe

Analyse Crystal structure of chicken sulfite oxidase mutant tyr 322 phe in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3HC2
Type: protein
Length: 372 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Sulfite oxidase
Ligands: MTE, MO
Pockets: 5 · best druggability 0.77

Structure

x-ray diffraction · 1 distinct chain · 13% helix, 35% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Sulfite oxidase	protein	372	13% helix, 35% strand	—

Ligands and binding sites

MTE · Phosphonic acidmono-(2-amino-5,6-dimercapto-4-oxo-3,7,8A,9,10,10A-hexahydro-4H-8-oxa-1,3,9,10-tetraaza-anthracen-7-ylmethyl)ester · ligand · chains A
MO · Molybdenum atom · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	89	0.77	0.98	22	MTE, MO
2	129	0.52	0.81	26	empty
3	83	0.40	0.78	21	empty
4	65	0.35	0.77	14	empty
5	51	0.24	0.72	14	empty

Compared structures

3HC2 · Crystal Structure of chicken sulfite oxidase mutant Tyr 322 Phe · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 3HC2 · PDBe 3HC2

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