Research workbench

Structure of recombinant chicken liver sulfite oxidase mutant C185S

Analyse Structure of recombinant chicken liver sulfite oxidase mutant C185S in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3HBG
Type: protein
Length: 353 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Sulfite oxidase mutant C185S
Ligands: MTE, MOM
Pockets: 2 · best druggability 0.70

Structure

x-ray diffraction · 1 distinct chain · 11% helix, 37% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Sulfite oxidase mutant C185S	protein	353	11% helix, 37% strand	—

Ligands and binding sites

MTE · Phosphonic acidmono-(2-amino-5,6-dimercapto-4-oxo-3,7,8A,9,10,10A-hexahydro-4H-8-oxa-1,3,9,10-tetraaza-anthracen-7-ylmethyl)ester · ligand · chains A
MOM · Hydroxy(dioxo)molybdenum · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	249	0.70	0.85	35	MTE, MOM
2	58	0.27	0.73	16	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

3HBG · Structure of recombinant Chicken Liver Sulfite Oxidase mutant C185S · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 3HBG · PDBe 3HBG

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.