Switching the chirality of the metal environment alters the coordination mode in designed peptides.

Structure

x-ray diffraction · 1 distinct chain · 90% helix, 0% strand (DSSP).

Ligands and binding sites

• ACE · Acetyl group · ligand · 3 copies · chains A, B, C
• ZN · Zinc ion · metal · 4 copies · chains A, C
• NH2 · Amino group · ion · 3 copies · chains A, B, C
• CL · Chloride ion · ion · 3 copies · chains A, B, C
• ACT · Acetate ion · additive · chains B, C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

3 interfaces between chains.

• A–C · 613 Ų buried · 5 hydrogen bonds · protein-protein
• B–C · 612 Ų buried · 2 hydrogen bonds · protein-protein
• A–B · 542 Ų buried · 1 hydrogen bond · protein-protein

Modifications

Observed in the structure: 3 covalent, 3 modified (covalent ligand, nonstandard).

Compared structures

• 3H5F · Switching the Chirality of the Metal Environment Alters the Coordination Mode in Designed… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Elsewhere: RCSB PDB 3H5F · PDBe 3H5F