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Crystal structure of the T. tengcongensis SAM-I riboswitch variant U34C/A94G mutant A6C/U7G/A87C/U88G bound with SAM

Analyse Crystal structure of the T. tengcongensis SAM-I riboswitch variant U34C/A94G… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3GX7
Type: RNA
Length: 94 nucleotides
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: RNA (94-mer)
Ligands: SAM, MG
Pockets: 3 · best druggability 0.75

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	RNA (94-mer)	rna	94	—	—

Ligands and binding sites

SAM · S-adenosylmethionine · ligand · chains A
MG · Magnesium ion · metal · 6 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1049	0.75	0.79	48	SAM, MG
2	602	0.64	0.76	30	MG
3	59	0.25	0.73	8	MG

Compared structures

3GX7 · Crystal structure of the T. tengcongensis SAM-I riboswitch variant U34C/A94G mutant… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 3GX7 · PDBe 3GX7

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