Research workbench
Chey-binding domain of chea in complex with chey from crystals soaked in acetyl phosphate
Analyse Chey-binding domain of chea in complex with chey from crystals soaked in acetyl… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1FFS
- Type
- protein
- Length
- 392 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Chemotaxis protein chey; Chemotaxis protein chea
- EC
- 2.7.3.-
- UniProt
- P06143, P07363
- Ligands
- MN
- Pockets
- 5 · best druggability 0.49
Structure
x-ray diffraction · 2 distinct chains · 40% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C | Chemotaxis protein chey (EC 2.7.3.-) | protein | 128 | 43% helix, 17% strand | P06143 |
| B, D | Chemotaxis protein chea | protein | 68 | 34% helix, 29% strand | P07363 |
Ligands and binding sites
- MN · Manganese (II) ion · metal · 2 copies · chains A, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 194 | 0.49 | 0.76 | 28 | empty |
| 2 | 141 | 0.47 | 0.77 | 23 | empty |
| 3 | 148 | 0.45 | 0.76 | 25 | empty |
| 4 | 55 | 0.29 | 0.75 | 11 | empty |
| 5 | 63 | 0.28 | 0.73 | 13 | empty |
Interfaces
3 interfaces between chains.
- C–D · 623 Ų buried · 7 hydrogen bonds · protein-protein
- A–B · 616 Ų buried · 7 hydrogen bonds · protein-protein
- A–C · 220 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 1FFS · Chey-binding domain of chea in complex with chey from crystals soaked in acetyl phosphate · the same entry in another collection · chain A against A, TM-score 1.00
- P07363 · AlphaFold monomer V2.0 prediction for chemotaxis protein chea (P07363) · a predicted model of the same protein · chain D against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P06143
- Every structure of UniProt P07363
- Elsewhere: RCSB PDB 1FFS · PDBe 1FFS · UniProt P06143 · UniProt P07363
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