Research workbench
Crystal structure of a putative translation initiation inhibitor from salmonella typhimurium
Analyse Crystal structure of a putative translation initiation inhibitor from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3GTZ
- Type
- protein
- Length
- 345 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative translation initiation inhibitor
- UniProt
- Q8ZP08
- Pockets
- 3 · best druggability 0.81
Structure
x-ray diffraction · 1 distinct chain · 30% helix, 36% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C | Putative translation initiation inhibitor | protein | 115 | 30% helix, 36% strand | Q8ZP08 |
Ligands and binding sites
- GOL · Glycerol · additive · chains A, B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 164 | 0.81 | 0.96 | 32 | GOL |
| 2 | 175 | 0.52 | 0.78 | 19 | empty |
| 3 | 191 | 0.49 | 0.76 | 16 | empty |
Interfaces
3 interfaces between chains.
- A–C · 1134 Ų buried · 16 hydrogen bonds · protein-protein
- A–B · 1129 Ų buried · 14 hydrogen bonds · protein-protein
- B–C · 866 Ų buried · 11 hydrogen bonds · protein-protein
Compared structures
- 3GTZ · Crystal structure of a putative translation initiation inhibitor from Salmonella… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8ZP08
- Elsewhere: RCSB PDB 3GTZ · PDBe 3GTZ · UniProt Q8ZP08
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