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Crystal structure of menaquinone-specific isochorismate synthase from yersinia pestis CO92

Analyse Crystal structure of menaquinone-specific isochorismate synthase from yersinia… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3GSE
Type: protein
Length: 425 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Menaquinone-specific isochorismate synthase
EC: 5.4.4.2
UniProt: Q0WDZ8
Ligands: SO4
Pockets: 4 · best druggability 0.70

Structure

x-ray diffraction · 1 distinct chain · 32% helix, 39% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Menaquinone-specific isochorismate synthase (EC 5.4.4.2)	protein	425	32% helix, 39% strand	Q0WDZ8

Ligands and binding sites

SO4 · Sulfate ion · ion · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	583	0.70	0.79	52	empty
2	123	0.47	0.78	27	empty
3	98	0.37	0.75	17	empty
4	51	0.27	0.75	14	empty

Compared structures

3GSE · Crystal structure of menaqui -specific isochorismate synthase from Yersinia pestis CO92 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q0WDZ8
Elsewhere: RCSB PDB 3GSE · PDBe 3GSE · UniProt Q0WDZ8

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