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Structure of the N-terminal heat domain of symplekin from D. melanogaster

Analyse Structure of the N-terminal heat domain of symplekin from D. melanogaster in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3GS3
Type: protein
Length: 249 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Symplekin
UniProt: Q8MSU4
Pockets: 1 · best druggability 0.53

Structure

x-ray diffraction · 1 distinct chain · 77% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Symplekin	protein	249	77% helix, 0% strand	Q8MSU4

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	184	0.53	0.78	21	empty

Compared structures

3GS3 · Structure of the N-terminal HEAT Domain of Symplekin from D. melanogaster · the same entry in another collection · chain A against A, TM-score 1.00
Q8MSU4 · AlphaFold monomer V2.0 prediction for symplekin (Q8MSU4) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8MSU4
Elsewhere: RCSB PDB 3GS3 · PDBe 3GS3 · UniProt Q8MSU4

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