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Crystal structure of the monomer of the P115 tether globular head domain

Analyse Crystal structure of the monomer of the P115 tether globular head domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3GRL
Type: protein
Length: 601 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: General vesicular transport factor P115
UniProt: P41541
Ligands: PO4
Pockets: 4 · best druggability 0.49

Structure

x-ray diffraction · 1 distinct chain · 71% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	General vesicular transport factor P115	protein	601	71% helix, 1% strand	P41541

Ligands and binding sites

PO4 · Phosphate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	90	0.49	0.82	21	empty
2	125	0.42	0.76	20	empty
3	146	0.41	0.75	20	empty
4	61	0.37	0.79	13	empty

Compared structures

3GRL · Crystal Structure of the Monomer of the p115 Tether Globular Head Domain · the same entry in another collection · chain A against A, TM-score 1.00
P41541 · AlphaFold monomer V2.0 prediction for general vesicular transport factor P115 (P41541) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P41541
Elsewhere: RCSB PDB 3GRL · PDBe 3GRL · UniProt P41541

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