Research workbench

Crystal structure of a transcriptional regulator, merr family from bacillus thuringiensis

Analyse Crystal structure of a transcriptional regulator, merr family from bacillus… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3GPV
Type: protein
Length: 231 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Transcriptional regulator, merr family
UniProt: Q6HKH9
Pockets: 2 · best druggability 0.30

Structure

x-ray diffraction · 2 distinct chains · 71% helix, 6% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Transcriptional regulator, merr family	protein	114	71% helix, 5% strand	Q6HKH9
B	Transcriptional regulator, merr family	protein	117	70% helix, 6% strand	Q6HKH9

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	50	0.30	0.75	10	empty
2	50	0.25	0.73	13	empty

Interfaces

1 interface between chains.

A–B · 1413 Å² buried · 2 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 12 modified (engineered).

Compared structures

3GPV · Crystal structure of a transcriptional regulator, MerR family from Bacillus thuringiensis · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6HKH9
Elsewhere: RCSB PDB 3GPV · PDBe 3GPV · UniProt Q6HKH9

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.