Research workbench
Crystal structure of ppic-type peptidyl-prolyl cis-trans isomerase domain at 1.55A resolution.
Analyse Crystal structure of ppic-type peptidyl-prolyl cis-trans isomerase domain at… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3GPK
- Type
- protein
- Length
- 216 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ppic-type peptidyl-prolyl cis-trans isomerase
- EC
- 5.2.1.8
- UniProt
- Q2G9Z0
- Ligands
- SO4
- Pockets
- 1 · best druggability 0.59
Structure
x-ray diffraction · 2 distinct chains · 40% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ppic-type peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) | protein | 108 | 42% helix, 31% strand | Q2G9Z0 |
| B | Ppic-type peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) | protein | 108 | 38% helix, 31% strand | Q2G9Z0 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 185 | 0.59 | 0.81 | 26 | empty |
Interfaces
1 interface between chains.
- A–B · 441 Ų buried · 3 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 modified (engineered).
Compared structures
- 3GPK · Crystal Structure of PpiC-type peptidyl-prolyl cis-trans isomerase domain at 1.55A… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q2G9Z0
- Elsewhere: RCSB PDB 3GPK · PDBe 3GPK · UniProt Q2G9Z0
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.